What do we know about long-term treatment outcomes for severe depressive disorders?

What do we know about long-term treatment outcomes for severe depressive disorders?

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In a recent issue of BJPsych Open, McPherson & Hengartner (see https://doi.org/10.1192/bjo.2019.65) reviewed 11 trials examining psychological and pharmacological treatment baby romper outcomes for chronic or treatment-resistant depression.

They concluded that when assessed in the long term, antidepressants become less effective whereas psychological therapies become more effective.We argue that the evidence does not support this; indeed, most of the studies reviewed do 2 Pack Tables not directly compare antidepressant with psychological therapy treatments and there is little consistency between them in terms of populations and interventions examined.The issue of long-term outcomes is key for optimising clinical guidelines and deserves more intensive research and scrutiny to improve patient response in routine practice.